(Senior) Principal - Clinical Outcome Assessment Science - Multiple locations in Europe - Hybrid/Home-based

IQVIA

Amsterdam

27 Mar 2026

Amsterdam

27 Mar 2026

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(Senior) Principal - Clinical Outcome Assessment Science - Multiple locations in Europe - Hybrid/Home-based

Senior/Principal Clinical Outcome Assessment Science role at IQVIA, focusing on COA endpoint strategy, regulatory engagement, and instrument development. Requires deep expertise in COA types, FDA interactions, and leadership in patient-centered research. Position is hybrid or home-based across multiple European locations.

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Hybrid

Full-time

Principal

Clinical Outcome Assessments

Patient-reported Outcomes

Salary

Not specified

Work Location

Amsterdam, North Holland, Netherlands, NL

Work Model

Hybrid or fully home-based across multiple European locations

Employment Type

Full-time

Experience Level

Senior/Principal

Core Qualifications

Technical (Must-have)

Clinical Outcome Assessmentspatient-reported outcomesqualitative researchquantitative researchendpoint strategyregulatory strategyCOA instrument developmentFDA engagementcontent validityclinical research

Soft Skills

leadershipmentoringcommunicationstakeholder engagementscientific writingpresentationentrepreneurialteamworkproblem solvingcritical thinking

Key Responsibilities

•Develop COA endpoint strategies across clinical development programs
•Bring senior COA expertise into client meetings, workshops, and strategic discussions
•Differentiate proposals and client solutions through expert-driven COA strategy narratives
•Translate emerging scientific and regulatory expectations into actionable client recommendations
•Advise sponsors on development and justification of COA endpoint strategies for regulatory interactions
•Support preparation for and participation in FDA meetings as the COA subject matter expert
•Guide sponsors on evidence expectations, context of use, and fit-for-purpose COA strategies
•Provide senior scientific leadership in the development of new COA instruments from concept to validation-ready tools
•Lead and advise on drafting and refinement of COA instrument items, response options, recall periods, and scoring approaches
•Oversee qualitative research activities supporting content validity, including concept elicitation and cognitive interviewing
•Ensure new COA instruments are patient-centered, scientifically robust, and fit-for-purpose for clinical and regulatory use
•Serve as subject matter expert overseeing internal project teams executing COA strategy and development work
•Review and approve key scientific deliverables to ensure quality, rigor, and alignment with best practices
•Mentor and coach COA scientists and consultants, supporting capability development across the organization
•Support business development through proposal leadership, solution design, and client presentations
•Contribute to the evolution of COA strategy methodologies, frameworks, and reusable assets
•Maintain a strong external profile through publications, conference presentations, and scientific collaborations
•Represent IQVIA as a recognized expert in COA science and endpoint strategy
•Contribute to academic teaching, advisory boards, or industry working groups where appropriate

Clinical Outcome AssessmentHealthcarePatient-Centered SolutionsRegulatory StrategyFDACOA ScienceSeniorPrincipalHybridEurope

Core Qualifications

Technical (Must-have)

Soft Skills

leadershipmentoringcommunicationstakeholder engagementscientific writingpresentationentrepreneurialteamworkproblem solvingcritical thinking

Key Responsibilities

•Develop COA endpoint strategies across clinical development programs

•Bring senior COA expertise into client meetings, workshops, and strategic discussions

•Differentiate proposals and client solutions through expert-driven COA strategy narratives

•Translate emerging scientific and regulatory expectations into actionable client recommendations

•Advise sponsors on development and justification of COA endpoint strategies for regulatory interactions

•Support preparation for and participation in FDA meetings as the COA subject matter expert

•Guide sponsors on evidence expectations, context of use, and fit-for-purpose COA strategies

•Provide senior scientific leadership in the development of new COA instruments from concept to validation-ready tools

•Lead and advise on drafting and refinement of COA instrument items, response options, recall periods, and scoring approaches

•Oversee qualitative research activities supporting content validity, including concept elicitation and cognitive interviewing

•Ensure new COA instruments are patient-centered, scientifically robust, and fit-for-purpose for clinical and regulatory use

•Serve as subject matter expert overseeing internal project teams executing COA strategy and development work

•Review and approve key scientific deliverables to ensure quality, rigor, and alignment with best practices

•Mentor and coach COA scientists and consultants, supporting capability development across the organization

•Support business development through proposal leadership, solution design, and client presentations

•Contribute to the evolution of COA strategy methodologies, frameworks, and reusable assets

•Maintain a strong external profile through publications, conference presentations, and scientific collaborations

•Represent IQVIA as a recognized expert in COA science and endpoint strategy

•Contribute to academic teaching, advisory boards, or industry working groups where appropriate